A Simple Key For cees dekker Unveiled
A Simple Key For cees dekker Unveiled
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‘The second is nanopores, which is our oldest line of study and which has now triggered DNA sequencers according to nanopores. We pull person DNA strands through a nanopore and may then study off the nucleotide sequence. Pretty recently, we even managed to browse out only one protein for The 1st time employing This method. But this line of analysis is not just about developing applications, but will also about true biological questions.
Our group experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that could autonomously divide. Our major curiosity lies in mobile division, chromatin framework, and spatial Handle.
, Groningen researchers current the final results in their efforts to create labs much more sustainable and provide strategies for other labs.
Considering that 2000, Dekker has shifted the most crucial target of his get the job done to biophysics in which he scientific tests the properties of single biomolecules and cells using the applications of nanotechnology. This transformation of subject was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as through the prolonged-time period standpoint that many fascinating discoveries could be predicted With this industry.[five] Present-day lines of analysis in his biophysics group are inside the regions of:[6]
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and to start with ever study on the dynamics DNA supercoils and the discovery of supercoil hopping
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
What distinguishes biology from chemistry is the fact these elements alongside one another make up a living system. The key of said daily life, I think, lies while in the interactions, the interaction of Individuals molecules. The massive query concerning the origin of lifetime is still unanswered. How did we ever evolve from very simple molecules in to the particularly complicated programs we see now? We have no idea. I would like to operate on these kinds of huge, open up concerns.’
2011, very first in vitro measurements of transport throughout only one biomimetic nuclear pore advanced; progress of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the mechanism of homology recognition in DNA homologous recombination
2003, demonstrated the main biosensors designed away from a carbon nanotube; solved the construction and mechanism of DNA maintenance proteins; and discovery of a completely new procedure for fabricating reliable-state nanopores for DNA translocation
Extremely interesting, but that wasn’t really the place my desire lay. I wanted to pioneer and I experienced the sensation which was no longer achievable, as the most interesting basic insights had by now been uncovered. But my field had designed quite a few fascinating new equipment to evaluate unique molecules. cees dekker I decided that I desired to implement this to biology, to have a look at it from the Actual physical point of view.’
Testing pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion against roadblock-traversal experiments
Character Physics thanks the nameless reviewers for their contribution into the peer overview of this get the job done.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style in 2005. (nl)